Test the labels on all of your medicines to find out if they incorporate acetaminophen, and request your pharmacist In case you are Doubtful.
The concomitant usage of PERCOCET with all cytochrome P450 3A4 inhibitors may perhaps lead to a rise in oxycodone plasma concentrations, which could enhance or lengthen adverse reactions and will trigger most likely fatal respiratory despair.
If concomitant use is warranted, commonly Appraise the affected person, specifically through therapy initiation and dose adjustment. Discontinue PERCOCET if serotonin syndrome is suspected.
If concomitant use is important, look at dosage reduction of oxycodone and acetaminophen tablets until secure drug outcomes are achieved. Check clients for respiratory depression and sedation at Recurrent intervals.
Acute or serious bronchial bronchial asthma in an unmonitored location or in the absence of resuscitative gear [see WARNINGS]
The bare minimum productive analgesic concentration of oxycodone for any personal affected individual may well improve as time passes on account of a rise in soreness, the development of a completely new agony syndrome, and/or the event of analgesic tolerance [see DOSAGE AND ADMINISTRATION].
In advance of using PERCOCET, tell your healthcare service provider When you've got a heritage of: Head damage, seizures
Emphasize to individuals as well as their caregivers the value of reading through the Medication Guideline that they may acquire from their pharmacist each and every time an opioid analgesic is dispensed to them.
Zidovudine The pharmacologic consequences of zidovudine could be decreased as a result of enhanced non-hepatic or renal clearance of zidovudine.
The pharmacologic effects of zidovudine can be lessened because of enhanced non-hepatic or renal clearance of zidovudine.
The concomitant usage of opioids with other opioid analgesics, for instance butorphanol, nalbuphine, pentazocine, may perhaps reduce the analgesic influence of oxycodone and acetaminophen tablets and/or precipitate withdrawal indications.
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Recommend patients to not execute this kind of tasks right until they understand how they're going to respond on the medication [see Safety measures].
Emphasize the importance of executing this ahead of an opioid emergency happens, Hence the individual and caregiver will know what to do.